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prelude x automated peptide synthesizer  (Gyros Protein Technologies)


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    Structured Review

    Gyros Protein Technologies prelude x automated peptide synthesizer
    Prelude X Automated Peptide Synthesizer, supplied by Gyros Protein Technologies, used in various techniques. Bioz Stars score: 96/100, based on 66 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prelude+x+peptide+synthesizer/Prelude+X/pmc13005684-211-8-13
    Average 96 stars, based on 66 article reviews
    prelude x automated peptide synthesizer - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    other:

    Article Title: GLP-1-directed NMDA receptor antagonism for obesity treatment
    Article Snippet: All peptides were prepared using ChemMatrix Rink amide resin and Fmoc-based automated peptide synthesis on a Prelude X peptide synthesizer (Gyros Protein Technologies) with induction heating and oscillation mixing.

    Article Title: GLP-1-directed NMDA receptor antagonism for obesity treatment.
    Article Snippet: All peptides were prepared using ChemMatrix Rink amide resin and Fmoc-based automated peptide synthesis on a Prelude X peptide synthesizer (Gyros Protein Technologies) with induction heating and oscillation mixing.

    Synthesized:

    Article Title: Affinity-Driven Aryl Diazonium Labeling of Peptide Receptors on Living Cells.
    Article Snippet: Peptide−receptor interactions play critical roles in a wide variety of physiological processes.. Methods to link bioactive peptides covalently to unmodified receptors on the surfaces of living cells are valuable for studying receptor signaling, dynamics, and trafficking and for identifying novel peptide−receptor interactions.. Here, we utilize peptide analogues bearing deactivated aryl diazonium groups for the affinity-driven labeling of unmodified receptors.

    Article Title: Synthetic Control of Tertiary Helical Structures in Short Peptides
    Article Snippet: .. The individual strands were synthesized on Prelude X peptide synthesizer (Gyros Protein Technologies) using standard Fmoc solid phase peptide synthesis and purified by reversed-phase HPLC. ..

    Article Title: Zwitterionic polymer-dexamethasone conjugates penetrate and protect cartilage from inflammation.
    Article Snippet: .. The peptide was synthesized using standard Fmoc solid phase chemistry on a Prelude X peptide synthesizer (Protein Technologies, Inc., Tucson, USA) at 500 μmol scale on a Rink Amide MBHA Resin (HL, 0.69 mmol/g, Gyros Protein Technologies, Uppsala, SWE). ..

    Article Title: DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.
    Article Snippet: .. 2018, 23 (5), 405– 416, DOI: 10.1177/2472555218757718 Solid-phase synthesis and purification General Fmoc Solid-Phase Peptide Synthesis (SPPS) procedure All peptides were synthesized on a Prelude X peptide synthesizer (Gyros Protein Technologies) using standard solid phase peptide synthesis chemistry (SPPS). .. Synthesis was carried out at 0.2 mmol scale for each compound on Fmoc-protected Rink Amide polystyrene resin (0.64 mmol/g, Rapp Polymere GmbH, 100-200 mesh).

    Article Title: Zwitterionic polymer-dexamethasone conjugates penetrate and protect cartilage from inflammation
    Article Snippet: .. The peptide was synthesized using standard Fmoc solid phase chemistry on a Prelude X peptide synthesizer (Protein Technologies, Inc., Tucson, USA) at 500 μmol scale on a Rink Amide MBHA Resin (HL, 0.69 mmol/g, Gyros Protein Technologies, Uppsala, SWE). ..

    Article Title: Influence of Charge Block Length on Conformation and Solution Behavior of Polyampholytes.
    Article Snippet: .. Solid-phase peptide synthesis (SPPS) and cleavage Sequence specific polyampholytes of increasing block size Np — (EK)16, (E2K2)8, (E4K4)4, (E8K8)2,and (E16K16) — as well as polyelectrolytes (E32 and K32) were synthesized using Fmoc-based SPPS on a Prelude X peptide synthesizer from Gyros Protein Technologies. .. Fmoc-based SPPS at 0.15 mmole scale was carried out on Rink Amide MBHA resin LL (Novabiochem) using Fmoc-L-Lys(Boc)-OH and Fmoc-L-Glu(OtBu)-OH amino acid reagents, O(6-Chloro- benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (HCTU) coupling reagent, and N-Methylmorpholine (NMM) base solution in N,N-Dimethylformamide (DMF) solvent from Gyros Protein Technologies at an excess of 4:3.93:7.86, respectively.1,2 The Fmoc groups were deprotected using two rounds of mixing with 20 % v/v piperi- S3 dine/DMF mixture (Gyros Protein Technologies) before each coupling and capped using a 25 % v/v acetic acid/DMF solution after each coupling past the 10th amino acid.

    Purification:

    Article Title: Synthetic Control of Tertiary Helical Structures in Short Peptides
    Article Snippet: .. The individual strands were synthesized on Prelude X peptide synthesizer (Gyros Protein Technologies) using standard Fmoc solid phase peptide synthesis and purified by reversed-phase HPLC. ..

    Article Title: DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.
    Article Snippet: .. 2018, 23 (5), 405– 416, DOI: 10.1177/2472555218757718 Solid-phase synthesis and purification General Fmoc Solid-Phase Peptide Synthesis (SPPS) procedure All peptides were synthesized on a Prelude X peptide synthesizer (Gyros Protein Technologies) using standard solid phase peptide synthesis chemistry (SPPS). .. Synthesis was carried out at 0.2 mmol scale for each compound on Fmoc-protected Rink Amide polystyrene resin (0.64 mmol/g, Rapp Polymere GmbH, 100-200 mesh).

    Reversed-phase High-Performance Liquid Chromatography:

    Article Title: Synthetic Control of Tertiary Helical Structures in Short Peptides
    Article Snippet: .. The individual strands were synthesized on Prelude X peptide synthesizer (Gyros Protein Technologies) using standard Fmoc solid phase peptide synthesis and purified by reversed-phase HPLC. ..

    Sequencing:

    Article Title: Influence of Charge Block Length on Conformation and Solution Behavior of Polyampholytes.
    Article Snippet: .. Solid-phase peptide synthesis (SPPS) and cleavage Sequence specific polyampholytes of increasing block size Np — (EK)16, (E2K2)8, (E4K4)4, (E8K8)2,and (E16K16) — as well as polyelectrolytes (E32 and K32) were synthesized using Fmoc-based SPPS on a Prelude X peptide synthesizer from Gyros Protein Technologies. .. Fmoc-based SPPS at 0.15 mmole scale was carried out on Rink Amide MBHA resin LL (Novabiochem) using Fmoc-L-Lys(Boc)-OH and Fmoc-L-Glu(OtBu)-OH amino acid reagents, O(6-Chloro- benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (HCTU) coupling reagent, and N-Methylmorpholine (NMM) base solution in N,N-Dimethylformamide (DMF) solvent from Gyros Protein Technologies at an excess of 4:3.93:7.86, respectively.1,2 The Fmoc groups were deprotected using two rounds of mixing with 20 % v/v piperi- S3 dine/DMF mixture (Gyros Protein Technologies) before each coupling and capped using a 25 % v/v acetic acid/DMF solution after each coupling past the 10th amino acid.

    Blocking Assay:

    Article Title: Influence of Charge Block Length on Conformation and Solution Behavior of Polyampholytes.
    Article Snippet: .. Solid-phase peptide synthesis (SPPS) and cleavage Sequence specific polyampholytes of increasing block size Np — (EK)16, (E2K2)8, (E4K4)4, (E8K8)2,and (E16K16) — as well as polyelectrolytes (E32 and K32) were synthesized using Fmoc-based SPPS on a Prelude X peptide synthesizer from Gyros Protein Technologies. .. Fmoc-based SPPS at 0.15 mmole scale was carried out on Rink Amide MBHA resin LL (Novabiochem) using Fmoc-L-Lys(Boc)-OH and Fmoc-L-Glu(OtBu)-OH amino acid reagents, O(6-Chloro- benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate (HCTU) coupling reagent, and N-Methylmorpholine (NMM) base solution in N,N-Dimethylformamide (DMF) solvent from Gyros Protein Technologies at an excess of 4:3.93:7.86, respectively.1,2 The Fmoc groups were deprotected using two rounds of mixing with 20 % v/v piperi- S3 dine/DMF mixture (Gyros Protein Technologies) before each coupling and capped using a 25 % v/v acetic acid/DMF solution after each coupling past the 10th amino acid.



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